Hanmin Huang
Professor of Organic Chemistry
State Key Laboratory for Oxo Synthesis and Selective Oxidation
Lanzhou Institute of Chemical Physics, CAS
18 Tianshui Middle Road, Lanzhou, 730000, P. R. China
Tel: 86-931-4968326
Email: hmhuang@licp.cas.cn
|
|
1. Transition-Metal-Catalyzed C-C and C-Heteroatom Bond Formation Reaction via Activation of Inert Chemical Bonds such as C-H and C-N Bond
2. Asymmetric Catalytic Synthesis
|
|
Education and Experiences
|
2008. 4- Professor, Lanzhou Institute of Chemical Physics, CAS
2004. 9~ 2008.3 Post-doctoral Fellow and JSPS Fellow, Research Center for Material Science, Nagoya University, Japan, with Prof. Masato Kitamura
2003. 10~ 2004. 8 Research Associate, Dalian Institute of Chemical Physics, CAS
2000. 8~ 2003. 10 Ph. D. Studies, Dalian Institute of Chemical Physics, CAS
|
1. Yinjun Xie, Yingwei Zhao, Bo Qian, Lei Yang, Chungu Xia, and Hanmin Huang*, Enantioselective N-H Functionalization of Indole with α,β-Unsaturated γ-Lactams Catalyzed by Brønsted Acids, Angew. Chem. Int. Ed. 2011, 50, 5682-5686.
2. Qiming Zhu, Dengjian Shi, Chungu Xia, Hanmin Huang*, Ruthenium Catalysts Containing Rigid Chiral Diamines and Achiral Diphosphanes for Highly Enantioselective Hydrogenation of Aromatic Ketones, Chem. Eur. J. 2011, 17, 7760-7763.
3. Yingwei Zhao, Jianping Shao, Hanmin Huang*, Chungu Xia*, Readily Available and Recoverable Chiral Ionic Phosphite Ligands for the Highly Enantioselective Hydrogenation of Functionalized Olefins, Tetrahedron: Asymmetry 2011, 22, (doi:10.1016/j.tetasy.2011.04.011), in press.
4. Bo Qian, Pan Xie, Yinjun Xie, and Hanmin Huang*, Iron-Catalyzed Direct Alkenylation of 2-Substituted Azaarenes with N-Sulfonyl Aldimines via C-H Bond Activation, Org. Lett. 2011, 13, 2580-2583.
5. Shengmei Guo, Bo Qian, Yinjun Xie, Chungu Xia, and Hanmin Huang*, Copper-Catalyzed Oxidative Amination of Benzoxazoles via C-H and C-N Bond Activation: A New Strategy for Using Tertiary Amines as Nitrogen Group Sources, Org. Lett. 2011, 13, 522-525.
6. Bo Qian, Shengmei Guo, Chungu Xia, and Hanmin Huang*, Lewis Acid-Catalyzed C-H Functionalization for Synthesis of Isoindolinones and Isoindolines, Adv. Synth. Catal. 2010, 352, 3195-3200.
7. Bo Qian, Shengmei Guo, Jianping Shao, Qiming Zhu, Lei Yang, Chungu Xia, and Hanmin Huang*, Palladium-Catalyzed Benzylic Addition of 2-Methyl Azaarenes to N-Sulfonyl Aldimines via C-H Bond Activation, J. Am. Chem. Soc. 2010, 132, 3650-3651.
8. Shengmei Guo, Yinjun Xie, Xinquan Hu, Chungu Xia, and Hanmin Huang*, Diastereo- and Enantioselective Catalytic Tandem Michael Addition/Mannich Reaction: Access to Chiral Isoindolinones and Azetidines with Multiple Stereocenters, Angew. Chem. Int. Ed. 2010, 49, 2728-2731.
9. Lei Yang, Qiming Zhu, Shengmei Guo, Bo Qian, Chungu Xia, and Hanmin Huang*, Chiral Bronsted Acid Directed Iron-Catalyzed Enantioselective Friedel-Crafts Alkylation of Indoles with β-Aryl α’-Hydroxy Enones, Chem. Eur. J. 2010, 16, 1638-1645.
10. Qiming Zhu, Hanmin Huang*, Dengjian Shi, Zhiqiang Shen, and Chungu Xia, An Efficient Synthesis of Chiral Diamines with Rigid Backbones: Application in Enantioselective Michael Addition of Malonates to Nitroalkenes, Org. Lett. 2009, 11, 4536.
11. Yinjun Xie, Hanmin Huang,* Weimin Mo, Xiangqun Fan, Zhiqiang Shen, Zhenlu Shen, Nan Sun, Baoxiang Hua, Xinquan Hu “Design and Synthesis of New Chiral Pyridine-Phosphite Ligands for the Copper-Catalyzed Enantioselective Conjugate Addition of Diethylzinc to Acyclic Enones” Tetrahedron: Asymmetry 2009, 20, 1425-1432.
12. Hanmin Huang, Tomoko Okuno, Kazuomi Tsuda, Masahiro Yoshimura, Masato Kitamura* “Enantioselective Hydrogenation of Aromatic Ketones Catalyzed by Ru Complexes of Goodwin-Lions-type sp2N/sp3N hybrid Ligands R-BINAN-R？-Py” J. Am. Chem. Soc.2006, 128, 8716-8717.
13. Hanmin Huang, Xiongcai Liu, Jun Deng, Min Qiu, Zhuo Zheng* “Rhodium-Catalyzed enantioselective Hydrogenation of β-Phthalimide Acrylates to Synthesis of β2-Amino Acids” Org. Lett. 2006, 8, 3359-3362.
14. Hanmin Huang, Xiongcai Liu, Huilin Chen, Zhuo Zheng* Monophosphite Ligands Derived from Carbohydrates and H8-BINOL: Highly Enantioselective Rh-Catalyzed Asymmetric Hydrogenations, Tetrahedron: Asymmetry 2005, 16, 693-697.
15. Hanmin Huang, Xiongcai Liu, Song Chen, Huilin Chen, Zhuo Zheng*, Carbohydrate-Drived Monophosphite ligands for Rh-Catalyzed Enantioselective Hydrogenation of α- and β-Dehydroamino Acid Esters, Tetrahedron: Asymmetry 2004, 15, 2011-2019.
16. Hanmin Huang, Zhuo Zheng,* Huili Luo, Changmin Bai, Xinquan Hu, Huilin Chen, A Novel Class of P-O Monophosphite Ligands Derived from d-Mannitol: Broad Applications in Highly Enantioselective Rh-Catalyzed Hydrogenations, J. Org. Chem. 2004, 69, 2355-2361.
17. Hanmin Huang, Huilin Chen, Xinquan Hu, Changmin Bai, Zhuo Zheng, Structure Probing of D-Fructose Derived Ligands for Asymmetric Addition of Diethylzinc to Aldehydes, Tetrahedron: Asymmetry 2003, 14, 297-304.
18. Hanmin Huang, Zhuo Zheng,* Huilin Chen, Changmin Bai, Junwei Wang, Readily available new pyridyl alcohols derived from D-glucose as ligands for the enantioselective addition of diethylzinc to aldehydes, Tetrahedron-Asymmetry 2003, 14, 1285-1289.
19. Hanmin Huang, Zhuo Zheng,* Huili Luo, Changmin Bai, Xinquan Hu, Huilin Chen*, Chiral Monophosphites Derived from Carbohydrate: Conformational Effect in Catalytic Asymmetric Hydrogenation, Org. Lett. 2003, 5, 4137-4139.
20. Masahiro Yoshimura, Toshimitsu Muraoka, Hiroshi Nakatsuka, Hanmin Huang, and Masato Kitamura* Synthesis of 3,3？-Diaryl-Substituted 2,2？-Diamino-1,1？-binaphthyl and Its Derivatives, J. Org. Chem. 2010, 75, 4315-4318. |
|
[中文] [English]